Recombivax HB, Hepatitis B Vaccine (Recombinant) Pediatric Formulation, 0.5 mL

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Description (Brief)
Recombivax HB is a vaccine that provides immunization against hepatitis B. It is injected intramuscularly. Recombivax HB is the first recombinant vaccine. Prior hepatitis B vaccines relied on viruses derived from human blood sources.
Recombinant pharmaceuticals are created by inserting genes from one species into a host species, often yeast or bacteria, where they do not naturally occur. The genes code for a desired product, and therefore the genetically modified host organisms can be grown and used as a kind of living factory to produce the product. In this case, genes coding for the hepatitis B virus's surface antigen are inserted into yeast. Yeast produce the hepatitis B surface antigens, which are harvested and used as the active ingredient in Recombivax HB. Surface antigens are the part of the hepatitis B virus that the body recognizes to create an immune response. After being exposed to the antigen, the body learns to identify and respond quickly to the presence of hepatitis B and can successfully ward off future possible infections.
Object consists of a white cardboard box with light blue stripes and light blue, red, and black printing. Box contains a product insert and a round clear glass bottle with metal top and white label. Bottle contains clear solution.
Location
Currently not on view
date made
ca 1988
product expiration date
1988-05-14
maker
Merck Sharp and Dohme
place made
United States: Pennsylvania, West Point
Physical Description
Hepatitis B surface antigen on alum adjuvant, 5 mcg (drug active ingredients)
Measurements
overall: 2 1/2 in x 1 5/16 in x 1 3/16 in; 6.35 cm x 3.33375 cm x 3.01625 cm
bottle: 3.3 mm x 1.4 cm; 1/8 in x 9/16 in
ID Number
1987.0782.01
accession number
1987.0782
catalog number
1987.0782.01
subject
Vaccines
See more items in
Medicine and Science: Medicine
Recombinant Pharmaceuticals
Science & Mathematics
Biotechnology and Genetics
Antibody Initiative: Infectious Disease, Allergy, and Immunotherapy Collections
Health & Medicine
The Antibody Initiative
Data Source
National Museum of American History, Kenneth E. Behring Center

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