Recombivax HB, Hepatitis B Vaccine (Recombinant) Pediatric Formulation, 0.5 mL

Description (Brief)
Recombivax HB is a vaccine that provides immunization against hepatitis B. It is injected intramuscularly. Recombivax HB is the first recombinant vaccine. Prior hepatitis B vaccines relied on viruses derived from human blood sources.
Recombinant pharmaceuticals are created by inserting genes from one species into a host species, often yeast or bacteria, where they do not naturally occur. The genes code for a desired product, and therefore the genetically modified host organisms can be grown and used as a kind of living factory to produce the product. In this case, genes coding for the hepatitis B virus's surface antigen are inserted into yeast. Yeast produce the hepatitis B surface antigens, which are harvested and used as the active ingredient in Recombivax HB. Surface antigens are the part of the hepatitis B virus that the body recognizes to create an immune response. After being exposed to the antigen, the body learns to identify and respond quickly to the presence of hepatitis B and can successfully ward off future possible infections.
Object consists of a white cardboard box with light blue stripes and light blue, red, and black printing. Box contains a product insert and a round clear glass bottle with metal top and white label. Bottle contains clear solution.
Object Name
pharmaceutical
vaccine
maker
Merck Sharp and Dohme
Physical Description
Hepatitis B surface antigen on alum adjuvant, 5 mcg (drug active ingredients)
Measurements
overall: 2 1/2 in x 1 5/16 in x 1 3/16 in; 6.35 cm x 3.33375 cm x 3.01625 cm
bottle: 3.3 mm x 1.4 cm; 1/8 in x 9/16 in
place made
United States: Pennsylvania, West Point
ID Number
1987.0782.01
accession number
1987.0782
catalog number
1987.0782.01
subject
Vaccines
Recombinant Pharmaceuticals
Biotechnology and Genetics
Health & Medicine
Science & Mathematics
See more items in
Medicine and Science: Medicine
Recombinant Pharmaceuticals
Biotechnology and Genetics
Exhibition
Birth of Biotech
Data Source
National Museum of American History, Kenneth E. Behring Center
Additional Media

Visitor Comments

Add a comment about this object

Submit a comment or ask a question about this object using the form below. Submissions are moderated and may receive a curator response. Please note that we cannot evaluate or appraise your personal artifacts. For other questions or general inquiries please visit our FAQ or contact page.

Personal information will not be shared or result in unsolicited e-mail. See our privacy policy.

Image CAPTCHA
Enter the characters shown in the image.