Recombivax HB, Hepatitis B Vaccine (Recombinant) Pediatric Formulation, 0.5 mL

Description (Brief)
Recombivax HB is a vaccine that provides immunization against hepatitis B. It is injected intramuscularly. Recombivax HB is the first recombinant vaccine. Prior hepatitis B vaccines relied on viruses derived from human blood sources.
Recombinant pharmaceuticals are created by inserting genes from one species into a host species, often yeast or bacteria, where they do not naturally occur. The genes code for a desired product, and therefore the genetically modified host organisms can be grown and used as a kind of living factory to produce the product. In this case, genes coding for the hepatitis B virus's surface antigen are inserted into yeast. Yeast produce the hepatitis B surface antigens, which are harvested and used as the active ingredient in Recombivax HB. Surface antigens are the part of the hepatitis B virus that the body recognizes to create an immune response. After being exposed to the antigen, the body learns to identify and respond quickly to the presence of hepatitis B and can successfully ward off future possible infections.
Object consists of a white cardboard box with light blue stripes and light blue, red, and black printing. Box contains a product insert and a round clear glass bottle with metal top and white label. Bottle contains clear solution.
Currently not on view
Object Name
date made
ca 1988
Merck Sharp and Dohme
Physical Description
Hepatitis B surface antigen on alum adjuvant, 5 mcg (drug active ingredients)
overall: 2 1/2 in x 1 5/16 in x 1 3/16 in; 6.35 cm x 3.33375 cm x 3.01625 cm
bottle: 3.3 mm x 1.4 cm; 1/8 in x 9/16 in
place made
United States: Pennsylvania, West Point
ID Number
accession number
catalog number
Recombinant Pharmaceuticals
Biotechnology and Genetics
Health & Medicine
Science & Mathematics
See more items in
Medicine and Science: Medicine
Recombinant Pharmaceuticals
Biotechnology and Genetics
Data Source
National Museum of American History, Kenneth E. Behring Center
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