Roferon-A, Interferon alfa-2a recombinant, Sterile Powder for Injection

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Description (Brief)
Roferon-A is an injectible, recombinant pharmaceutical used to treat different types of leukemia, malignant melanoma, multiple myeloma, non-Hodgkin's lymphoma, AIDS-related sarcoma, and hepatitis. It was discontinued in October 2007, as new therapies for the diseases it treated were developed.
Recombinant pharmaceuticals are created by inserting genes from one species into a host species, often yeast or bacteria, where they do not naturally occur. The genes code for a desired product, and therefore the genetically modified host organisms can be grown and used as a kind of living factory to produce the product. In this case, genes coding for human interferon are inserted into bacteria. Interferon is a substance that is naturally made by the body to fight infections and tumors. Bacteria produce the interferon, which is harvested and used as the active ingredient in Roferon-A.
Object consists of a sealed white cardboard box with red and black print.
Location
Currently not on view
date made
ca 1988
product expiration date
1988-06-01
maker
Hoffmann-La Roche
Roche Laboratories
place made
United States: New Jersey, Nutley
Physical Description
interferon alfa-2a, recombinant, 18 million iu (drug active ingredients)
Diluent for Roferon-A, 3 mL (drug active ingredients)
Measurements
overall: 2 in x 2 9/16 in x 1 5/16 in; 5.08 cm x 6.50875 cm x 3.33375 cm
overall: 2 in x 2 1/2 in x 1 3/8 in; 5.08 cm x 6.35 cm x 3.4925 cm
ID Number
1987.0786.03
accession number
1987.0786
catalog number
1987.0786.03
Credit Line
Hoffmann-La Roche, Inc.
See more items in
Medicine and Science: Medicine
Recombinant Pharmaceuticals
Science & Mathematics
Biotechnology and Genetics
Health & Medicine
The Antibody Initiative
Antibody Initiative: Monoclonal Antibodies
Data Source
National Museum of American History, Kenneth E. Behring Center

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