Eco RI

Description (Brief)
This silver metal canister once contained Eco RI, an enzyme commonly used in molecular biology. Eco RI belongs to a class of enzymes known as restriction enzymes, which are useful for their ability to cleave DNA only at locations containing specific sequences of nucleotides, the small chemical units that make up the longer DNA molecule. Eco RI recognizes the sequence GAATTC and will cut between the G and first A.
This particular canister of Eco RI was used to create recombinant DNA molecules at Genentech, a biotechnology company, in the early 1980s.
National Library of Medicine Medical Subject Headings. “Deoxyribonuclease EcoRI.”
Currently not on view
Object Name
Eco RI
date made
Genentech, Inc.
Physical Description
solution in potassium phosphate, 10 mmol/l (overall active ingredients)
NaCl, 0.2 mol/l (overall active ingredients)
dithiothreitol, 0.5 mmol/l (overall active ingredients)
Triton X-100, 0.2% (v/v) (overall active ingredients)
glycerol, 50% (v/v) (overall active ingredients)
EDTA, 1 mmol/l (overall active ingredients)
metal (overall material)
Eco RI high concentration (overall active ingredients)
overall: 2 7/8 in x 1 1/4 in; 7.3025 cm x 3.175 cm
place made
Bundesrepublik Deutschland
United States: California, South San Francisco
ID Number
accession number
catalog number
Science & Mathematics
Biotechnology and Genetics
See more items in
Medicine and Science: Biological Sciences
Biotechnology and Genetics
Data Source
National Museum of American History, Kenneth E. Behring Center
Credit Line
Gift of Genentech
Additional Media

Visitor Comments

Add a comment about this object

**Please read before submitting the form**

Have a comment or question about this object to share with the community? Please use the form below. Selected comments will appear on this page and may receive a museum response (but we can't promise). Please note that we generally cannot answer questions about the history, rarity, or value of your personal artifacts.

Have a question about anything else, or would you prefer a personal response? Please visit our FAQ or contact page.

Personal information will not be shared or result in unsolicited e-mail. See our privacy policy.

Enter the characters shown in the image.