Smeloff-Cutter Heart Valve

This caged ball valve was developed by Dr. Edward Smeloff. The struts are thick and flat, which was disadvantageous because it made clotting more likely. The struts at the top and bottom remain open and unconnected to the lower surface area. It has a titanium skeleton with a silastic ball and a Teflon sewing ring. Its advantages are long term durability and good hemodynamics. The disadvantages are a high embolic rate and the need to take an anticoagulant. A 1975 study on 200 patients who received this implant yielded a hospital mortality rate of 22% and a thromboembolic complication rate of 15%. Another study of 134 patients with a mean age of 54 years and aortic stenosis as the dominant issue yielded an 85% survival rate of 5 years and a 75% survival rate of eight years. Its main structural problem is that of ball variance, but it has an advantage over disc valves with a lower rate of thrombotic stenosis.
Dr. Edward Smeloff (1925-2012) worked with the engineering department at Sacramento State College to develop a mechanical heart. The Smeloff-Cutter valve was manufactured by Cutter Laboratories, a family-owned pharmaceutical company in Berkeley, California founded by Edward Ahern Cutter in 1897.
Currently not on view
Object Name
artificial heart valve
date made
after 1966
Cutter Laboratories, Inc.
Physical Description
titanium (valve material)
cloth (valve material)
silastic (valve material)
valve: 3.2 cm x 2.6 cm; 1 1/4 in x 1 1/32 in
place made
United States: California, Berkeley
ID Number
catalog number
accession number
Health & Medicine
Artificial Heart Valves
Artificial Organs
See more items in
Medicine and Science: Medicine
Artificial Heart Valves
Data Source
National Museum of American History, Kenneth E. Behring Center
Credit Line
Gift of Manuel Villafaña
Additional Media

Visitor Comments

2/1/2017 6:51:30 PM
Madonna Borromeo
I worked at Cutter Lab for 5 years back in the 70's...I still have my 5 year pin. I polished hundreds of these valves after they came in from the filers. They were one of the harder ones to polish because they came in different sizes, the baby valve was the hardest but the prettiest....because the struts were so close together. Sometimes we had to re-work them several times without scraping them to pass QA inspection. I especially loved polishing baby valve but liked all the others Cutter produced...I miss working there but thank goodness for the memories
Add a comment about this object

**Please read before submitting the form**

Have a comment or question about this object to share with the community? Please use the form below. Selected comments will appear on this page and may receive a museum response (but we can't promise). Please note that we generally cannot answer questions about the history, rarity, or value of your personal artifacts.

Have a question about anything else, or would you prefer a personal response? Please visit our FAQ or contact page.

Personal information will not be shared or result in unsolicited e-mail. See our privacy policy.

Enter the characters shown in the image.