666 Cold Preparation

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The indications or uses for this product as provided by the manufacturer are:
Aids in relieving distress and discomforts of colds by its fourfold action -- as an analgesic, as an antipyretic, as an expectorant, and as a laxative. For relief of coughs, simple headaches and neuralgia, muscular aches, pains, and reducing fever due to colds.
Currently not on view
date made
after 1938
Sherman Pharmacy
Monticello Drug Company
place made
United States: Florida, Jacksonville
Physical Description
cardboard (box material)
glass (bottle material)
plastic (cap material)
antipyrine (drug active ingredients)
ammonium chloride (drug active ingredients)
magnesium sulphate (drug active ingredients)
citric acid (drug active ingredients)
box: 6 5/8 in x 2 3/8 in x 1 5/8 in; 16.8275 cm x 6.0325 cm x 4.1275 cm
bottle: 6 1/4 in x 2 1/4 in x 1 1/2 in; 15.875 cm x 5.715 cm x 3.81 cm
ID Number
accession number
catalog number
Credit Line
Gift of Alan & Elaine Levitt
Catarrh, Cough & Cold Drugs
Pain & Neuralgia Drugs
See more items in
Medicine and Science: Medicine
Health & Medicine
Balm of America
Sherman Pharmacy, Sherman, New York
Data Source
National Museum of American History


This product was a staple in my home. Just before the winter got really cold, we had a “ med” day, It was a dose of 666, castor oil, or cod liver oil. You picked your poison. I always opted for the 666. It made me quiver, break out in chills, but was most effective. My mother gave us a orange wedge to kill the taste, which never worked.
As a senior in college I contracted the worst case of flu I ever had...fever, headache, muscular aches and pains, cough...you name it, I had it....everything except diarrhea....my grandmother gave me 4 tablespoons of 666....tasted like kerosine....20 minutes later it hit me like a runaway semi...vomited and defecated for the next 12 hours...the cure almost killed me....but I was back to normal the next day....great stuff if it doesn’t kill you...!!!
Back in the 70s when people WERE DYING from Swine flu, Our mother used 666s to treat my baby sister for 2 weeks. She was down hard, but that tonic took care of business!
Bring it Back!!!! Please, this product works. Nasty but works.
I agree with the above comment, but I'd go one step further to say it was made by satan, for satan; but the stuff worked. My mom and dad used to give it to my brother and I when we were kids also. It worked when nothing else would. That, along with raw onions wrapped in a handkerchief placed around our foreheads for fever, and Vicks Vapor rub on our chest and throats. We smelled like a cross between a medicine chest and a sub shop! LOL I can't find it anywhere in Baltimore, or online. These new products on the market just don't work as good as those three sixes.
Why the name 666?
Why can't I find 666 cold preparation. It worked wonders for a cold.
This stuff is a miracle drug. My grandmother used to give it to us as children. It tastes like dish soap, but is very effective for all sorts of ailments.
You can probably find some out in small cornerstores in the country. I live in SC, and where my parents are from (small country town) , I am still able to purchase it. Heard it used to taste horrible, but it tastes great these days.
Reading my grandfather's journal from 1921 where in he stated that he purchased 666 medication from a pharmacy in South Carolina for severe headaches since no doctor was available to see him.
666 must have been made by satan himself. My parents gave this to my Brother and I when we had colds. It is the worse thing I have ever tasted. It was a very popular cold remedy. I just read it also had a laxative effect. It's a wonder were survived childhood back then..

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