Watson and Crick Metal Base Pair from Model

Description
This is one of four brass templates illustrating the base pairings of adenine and thymine or cytosine and guanine, from Francis Crick's and James Watson's original model of the "double helix" of DNA. Two templates show the correct base pair shapes; two others are earlier, misconceived models. Watson and Crick's story of discovery is well told in James Watson's The Double Helix, including the moment they put together the first correct model. A key clue for matching the correct forms of adenine and thymine or guanine and cytosine came from American crystallographer Jerry Donohue, who worked in the same laboratory as Watson and Crick. Data from Donohue and other crystallographers, including Rosalind Franklin, was key to Watson and Crick’s success. After the double helix research was published in Nature, generating tremendous worldwide notoriety, Donohue kept the model templates as souvenirs. Later, he returned to the United States, taking a position at the Fox Chase Cancer Center in Philadelphia. Shortly before his death, Donohue gave the templates to his friend and fellow crystallographer, Dr. Helen Berman, who presented them to the Smithsonian in 1988.
Location
Currently not on view
Object Name
model part
template
DNA model template
Date made
1953
originator
Crick, Francis
Watson, James
maker
Cavendish Laboratory
Physical Description
brass (overall material)
Measurements
overall: 2 cm x 24 cm x 8 cm; 13/16 in x 9 7/16 in x 3 1/8 in
ID Number
1988.0494.01
accession number
1988.0494
catalog number
1988.0494.01
subject
Science & Mathematics
See more items in
Medicine and Science: Medicine
Data Source
National Museum of American History, Kenneth E. Behring Center

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