Actimmune, Interferon gamma-1b injection

Description (Brief):

Actimmune is a recombinant pharmaceutical used to treat children and adults with chronic granulomatous disease (CGD, an immune system disorder) and severe, malignant osteopetrosis (a disease which causes bones to become extremely dense and can lead to blindness, scoliosis, and a number of other problems).

Description (Brief)

Recombinant pharmaceuticals are created by inserting genes from one species into a host species, often yeast or bacteria, where they do not naturally occur. The genes code for a desired product, and therefore the genetically modified host organisms can be grown and used as a kind of living factory to produce the product. In this case, genes coding for human interferon are inserted into bacteria. Interferon is a substance that is naturally made by the body to fight infections and tumors. Bacteria produce the interferon, which is harvested and used as the active ingredient in Actimmune.

Description (Brief)

Object is a plastic clamshell-style box with tabs for opening labeled "HOLD" and "LIFT." Box contains 12 single-dose vials, which are round, clear glass bottles with blue plastic tops and white labels with black and green printing.

Date Made: before November 1993

Maker: Genentech, Inc.

Location: Currently not on view

Place Made: United States: California, South San Francisco

See more items in: Medicine and Science: Medicine, Health & Medicine, The Antibody Initiative, Biotechnology and Genetics, Recombinant Pharmaceuticals, Science & Mathematics, Antibody Initiative: Monoclonal Antibodies


Exhibition Location:

Data Source: National Museum of American History

Id Number: 2012.0046.49Accession Number: 2012.0046Catalog Number: 2012.0046.49

Object Name: biologicalpharmaceutical, recombinant

Measurements: overall: 1 3/4 in x 4 1/8 in x 3 5/8 in; 4.445 cm x 10.4775 cm x 9.2075 cmoverall: 1 3/4 in x 4 1/8 in x 3 3/4 in; 4.445 cm x 10.4775 cm x 9.525 cm


Record Id: nmah_1421748

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