A spectrophotofluorometer is a complex instrument that measures the spectrum of fluorescent light reflected from a substance of interest. Robert L. Bowman and Sidney Udenfriend, a physician and a biochemist working at the National Heart Institute in the early 1950s, designed and tested the form. They then worked with Hugh King Howerton, an American Instrument Company physicist, to develop the instrument that was put on the market in 1956.

The inscriptions on this example read: “American Instrument Co., Aminco, Silver Spring Maryland No. D223-62155 Serial . . .” and “Aminco-Bowman Spectrophotofluorimeter / American Instrument Company, Inc. / Silver Spring, Maryland, U.S.A. / Made in U.S.A. accordance with Patent Nos. 2,971.429 and 3,092,722.”

Ref: H. K. Howerton, “Spectro-Fluorescence Measuring Instrument,” U.S. Patent 2,971,429 (Feb. 1, 1961), assigned to American Instrument Company, Inc.

H. K. Howerton, “Spectro-Fluorescence Measuring Instrument,” U.S. Patent 3,092,722 (June 4, 1963), assigned to American Instrument Company, Inc.

Sidney Udenfriend, “Development of the spectrophotofluorometer and its commercialization,” Protein Science 4 (1995): 542-551.

Date Made: 1963-1970

Maker: American Instrument Company

Location: Currently not on view

Place Made: United States: Maryland, Silver Spring

Subject: Science & Scientific Instruments


See more items in: Medicine and Science: Chemistry


Exhibition Location:

Credit Line: Transfer from NIH

Data Source: National Museum of American History

Id Number: 1981.0535.04Catalog Number: 1981.0535.04Accession Number: 1981.0535

Object Name: spectrophotofluorimeter

Measurements: overall: 45.1 cm x 70.3 cm x 44 cm; 17 3/4 in x 27 11/16 in x 17 5/16 inoverall:;overall: 53 in x 39 in x 89 in; 134.62 cm x 99.06 cm x 226.06 cm

Guid: http://n2t.net/ark:/65665/ng49ca746a0-ecd6-704b-e053-15f76fa0b4fa

Record Id: nmah_397

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