Enovid-E 21 Oral Contraceptive

Enovid-E 21 Oral Contraceptive

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Description (Brief)
The popularity of “the Pill” created a new market for pharmaceutical companies. For the first time, healthy women would be taking medication for an extended period of time. Pill manufacturers developed unique packaging in order to distinguish their product from those of their competitors and build brand loyalty. Packaging design often incorporated a “memory aid” to assist women in tracking their daily pill regimen, as well as styled cases to allow pills to be discreetly carried in bags and purses. The National Museum of American History’s Division of Medicine and Science’s collection of oral contraceptives illustrates some of the changes that the packaging and marketing of the Pill underwent from its inception in 1960 to the present.
G. D. Searle and Company of Chicago, Illinois, produced this Enovid-E 21 brand oral contraceptive around 1975. This 21-pill blister pack is in Searle’s trademarked Compack plastic case. The gold-foil blister pack organizes the monthly dosage into three weekly rows, with each column labeled for the day of the week. The pack includes a pamphlet directing patients on proper usage.
Currently not on view
Object Name
contraceptive, oral
date made
ca 1975
G. D. Searle and Company
place made
United States: Illinois, Chicago
Physical Description
norethynodrel, 2.5 mg (drug active ingredients)
mestranol, 0.1 mg (drug active ingredients)
overall (folded): 11.1 cm x 12.6 cm x 1.4 cm; 4 3/8 in x 4 31/32 in x 9/16 in
pill pack (open): 10.6 cm x 10.5 cm x.5 cm; 4 3/16 in x 4 1/8 in x 3/16 in
overall, as stored: 3/8 in x 10 in x 4 1/2 in;.9525 cm x 25.4 cm x 11.43 cm
ID Number
catalog number
accession number
Credit Line
Gift of Gladys Abell and Lester D. Johnson, Jr., M.D.
Birth Control/Contraception
Women's Health
See more items in
Medicine and Science: Medicine
Birth Control
Health & Medicine
Data Source
National Museum of American History
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I took Enovid-E from 1980 until they quit making it. I felt better on it than any other BCP or HRT combination since then.
My mother took me to her (male) gynecologist in 1964 when I was 16 because when I started my periods at 14, the next one wasn't until six months later and that pattern continued. The gyno put me on Enovid-E, which I took for five years. My periods were of course regular, and when I stopped at age 21 and in a relationship, I didn't use any birth control. It took a year before I got pregnant. At some point Enovid-E was taken off the market....I've had a problem with Estrogen ever since I took it.

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