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Braunwald-Cutter Heart Valve

Braunwald-Cutter Heart Valve

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These are two open-caged ball valves have silastic or silicone rubber poppets. This was the first time a valve had cloth-covered struts. The reasoning behind this design was that Dr. Nina Starr Braunwald one of its creators, believed it would reduce clot formation because tissue infiltrated the fabric. However, fabric covered metal actually increased thrombogenicity, and clots soon covered by endothelial cells, yielded a non-thrombogenic surface. According to the donor Manny Villafana the Braunwald-Cutter Valve is an example of good engineering that failed.
In 1967, Braunwald began work in conjunction with Cutter Laboratories to develop this cloth covered caged ball valve, using Dacron fabric and polypropylene mesh. It had good hemodynamics and was made of polypropylene over titanium, a silastic poppet, and polypropylene mesh. These two valves were previously implanted in people and then explanted. The large valve shows wear/variance on the poppet as well as a large crack. The mesh on the struts has worn down or completely come off. The small valve also shows wear of the cloth from the struts. Clinical use of the valve began in 1968 and lasted until 1979, when there were a significant number of cases of fabric wear, poppet abrasion, and poppet escape.
Dr. Nina Starr Braunwald (1928-1992) led the surgical team that was the first to implant a prosthetic heart valve, which she also designed (1960). She received her MD from New York University School of Medicine and was one of the first women to train as a general surgeon at New York's Bellevue Hospital, from 1952 to 1955. She completed her training in general surgery and her residency at Georgetown University Medical Center, with a postdoctoral fellowship in Dr. Charles Hufnagel's surgical laboratory.
From 1958 to 1968 Dr. Braunwald practiced at the National Heart Institute (now the National Heart, Lung and Blood Institute) of the National Institutes of Health (NIH) in Bethesda, Maryland. From 1958 to 1965 she served as the chief of surgery. While at the NIH she developed her caged ball artificial heart valve, (the Braunwald-Cutter valve) which was implanted in patients during the late 1960s and early 1970s. In 1972, Dr. Braunwald joined the faculty at Harvard Medical School. She was the first woman to be elected to the American Association for Thoracic Surgery.
Currently not on view
Object Name
artificial heart valve
date made
ca 1970
Cutter Laboratories, Inc.
place made
United States: California, Berkeley
Physical Description
silicone rubber (overall material)
dacron (overall material)
polypropylene mesh (overall material)
titanium (overall material)
silastic (overall material)
overall: 3.5 cm x 4.1 cm x 4.1 cm; 1 3/8 in x 1 5/8 in x 1 5/8 in
ID Number
catalog number
accession number
Credit Line
Gift of Manuel Villafaña
Artificial Organs
See more items in
Medicine and Science: Medicine
Artificial Heart Valves
Health & Medicine
Data Source
National Museum of American History
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