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Usage conditions apply
The indications or uses for this product as provided on its packaging:
For nervous affections, facial neuralgia, locomotor ataxia [inability to control movement], sciatica; intensive reflex headaches, and in headaches of various sorts.
Administration: Dissolve in boiling water; stir; cool down to comfortable warmth for swallowing; sweeten to taste. If Whisky or Brandy is used as a solvent, NO HEAT is needed.
Antefebrin was the brand name of the chemical acetanilide produced by Kalle & Company of Biebrich, Germany as an antipyretic [fever reducer] and analgesic. In 1886, Drs. Cahn and Hepp discovered acetanilide’s ability to reduce fever and relieve pain, branding their new discovery Antefebrin. Dosage was one ounce dissolved in boiling water or alcohol and taken every twenty to thirty minutes while symptoms persist. Kalle & Company was purchased by Hoechst in 1908. This container dates between 1906 and 1908.
Object Name
Other Terms
Patent Medicines; Drugs; Non-Liquid
date made
Kalle and Company
place made
Germany: Hesse, Wiesbaden
Physical Description
acetanilid (drug active ingredients)
overall: 2 7/8 in x 2 1/8 in x 1 in; 7.3025 cm x 5.3975 cm x 2.54 cm
ID Number
accession number
catalog number
Credit Line
Gift of Robert J. Locurto
See more items in
Medicine and Science: Medicine
Health & Medicine
American Enterprise
American Enterprise
Exhibition Location
National Museum of American History
Data Source
National Museum of American History
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Hello, My reading of the container is that the dosage is between about 500 and 1000 mg. For example, for headaches of various sorts, "gr. viii-x" would be 8-10 grains, where a grain is about 65 mg. Thank you for maintaining this on-line resource.

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